PM s without judgement, soon without power?

Power Systems Without Fuel

The finiteness of fossil fuels implies that future electric power systems may predominantly source energy from fuel-free renewable resources like wind and solar. Evidently, these power systems without fuel will be environmentally benign, sustainable, and subject to milder failure scenarios. Many of these advantages were projected decades ago with the definition of the soft energy path, which de...

Isolated Papillary Muscle (PM) hypertrophy is characterized by an asymmetric hypertrophy of one PM without hypertrophy

Isolated Papillary Muscle (PM) hypertrophy has been supposed to be a phenotypic variant of hypertrophic cardiomyopathy. Whether this finding may explain an electrocardiographic pattern of left ventricular hypertrophy has to be demonstrated. A cardiac magnetic resonance imaging may add additional crucial information. Our case was a 26-year-old asymptomatic male cyclist who underwent routine spor...

S ccess without U…. Tough

Remodelling without a power stroke.

DNA within eukaryotic organisms is packaged into chromatin, which helps organization and compaction of the genetic material in the limited space within the nucleus. However, for efficient transcription, nucleosome positioning must be dynamically regulated, either allowing access to the transcription machinery or to block spurious gene expression [1]. Nucleosomes are inherently stable structures...

Power Is Nothing Without Control

Cardiac cell–based therapy, after a peak of untimely expectations of miraculous efficacy exceeding standard clinical practice, has faced the cardiological community and funding bodies with a predictable trough of disillusionment. In the light of more recent progresses, the field is by contrast moving toward a competitive differentiation phase, in which the resolution of the complex matching bet...